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Table 2 Univariate random-effects models for abdominal pain severity (β1) with age as predictor (β2) and with covariates (β3) individually entered

From: Abdominal pain during the menopause transition and early postmenopause: observations from the Seattle Midlife Women’s Health Study

 

Mean Values

Standard Deviations

Number

(p - values)

Intercept

Slope

Covariate

ntercept

Slope

Residual Error

 

Predictor

β1a

β2a

β3a

σ1b

σ2b

σ3b

Women

Observations

Age (47.6 years)

0.23

−.003 (0.220)

0.29

0.02

0.36

291

6977

Reproductive Aging Markers

 Late Reproductive c

0.24 (<  0.001)

−0.001 (0.750)

 

0.29

0.02

0.36

291

6977

 Early MT

  

− 0.001 (0.970)

     

 Late MT

  

−0.007 (0.780)

     

 Early PM

  

− 0.04 (0.160)

     

 Urinary Estrone (ng/mg creatinine, Log10)

0.20 (<  0.001)

− 0.01 (<  0.001)

− 0.04 (0.020)

0.28

0.01

0.35

131

4908

 Urinary FSH (mIU/mg creatintine, Log10)

0.20 (<  0.001)

−0.01 (<  0.001)

− 0.004 (0.720)

0.28

0.02

0.35

131

4996

 Urinary Testosterone (ng/mg creatinine, Log10)

0.20 (<  0.001)

−0.01 (<  0.001)

− 0.03 (0.020)

0.28

0.02

0.35

131

4975

Stress-related Biomarkers

 Urinary Cortisol (ng/mg creatinine, Log10)

0.20 (<  0.001)

−0.01 (<  0.001)

− 0.01 (0.310)

0.28

0.02

0.35

131

4993

 Urinary Epinephrine (ng/mg creatinine, Log10)

0.20 (<  0.001)

−0.01 (<  0.001)

0.0004 (0.940)

0.28

0.01

0.35

130

3325

 Urinary Norepinephrine (ng/mg creatinine, Log10)

0.20 (<  0.001)

−0.01 (<  0.001)

0.005 (0.820)

0.27

0.01

0.35

130

3329

Stress-related Perceptions

 Perceived Stress (1–6)

0.21 (<  0.001)

− 0.003 (0.280)

0.009 (0.060)

0.29

0.02

0.36

291

6977

 Tension (0–4)

0.20 (<  0.001)

−0.003 (0.190)

0.05 (< 0.001)

0.28

0.02

0.36

291

6977

 Anxiety (0–4)

0.19 (<  0.001)

−0.003 (0.190)

0.06 (< 0.001)

0.27

0.02

0.36

291

6977

  1. a β1, β2, β3 are the fixed effects (group averages) for the intercept, slope and covariate, respectively. β1 represents the mean value in abdominal pain severity for all women in the sample at the mean centered age (47.6 years); β2 represents the rate and direction (+ or -) of change in abdominal pain severity per year; and β3 represents the change in mean abdominal pain severity score for every unit of change in covariate score, when the covariate is added to the model
  2. b σ1, σ2, σ3 are the random effects (variability) for the intercept, slope and residual error, respectively
  3. c Reference group for this categorical variable